Vitamin E Research Today is a free monthly online journal that collates and summarizes the latest research about Vitamin E, including details on benefits, dosage, supplements, antioxidants.

Effects of alpha-tocopherol and related compounds on reactions involving various organic radicals.

Povalishev VN, Polozov GI, Shadyro OI

Department of Chemistry, Belarussian State University, Nezavisimosti av., 4, 220050 Minsk, Republic of Belarus.

Effects of alpha-tocopherol, PMC, and a number of the respective sulfur-containing analogues on reactions involving various organic radicals were studied. The test compounds were found to interact with alkyl radicals more effectively than with peroxyl radicals. The presence of a sulfur atom in structures of the respective analogues did not produce significant effects on reactivity. Derivatives of 5-hydroxy-1,3-benzoxathiol-2-one and 6-hydroxy-1,4-benzoxathiin-2(3H)-one displayed a high reactivity toward alpha-hydroxyalkyl radicals.

Published 27 January 2006 in Bioorg Med Chem Lett, 16(5): 1236-9.
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