The transcriptional signature of vitamin E.
Johnson A, Manor D
Division of Nutritional Sciences, Cornell University, Ithaca, NY 14853, USA.
To investigate the ability of RRR-alpha-tocopherol to regulate gene expression, we interrogated RNA samples from treated cultured cells with Affymetrix oligonucleutodie arrays. We find that vitamin E potently regulates the expression of ca. 230 genes, functioning in metabolism, cell-cycle progression, and transcriptional regulation.
Published 8 March 2005 in Ann N Y Acad Sci, 1031: 337-8.
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