Vitamin E Research Today is a free monthly online journal that collates and summarizes the latest research about Vitamin E, including details on benefits, dosage, supplements, antioxidants.

Evolution of serum alpha-tocopherol in the postprandial and postabsorptive phases in type 1 diabetes mellitus.

Manuel-y-Keenoy B, Van Campenhout A, Vertommen J, Van Gaal L, De Leeuw I

University of Antwerp (UA) campus Drie Eiken, Metabolic Research Unit (AMRU) T4.37, Universiteitsplein 1, B-2610 Wilrijk-Antwerp, Belgium. begona.manuelykeenoy@ua.ac.be

Blood glucose, lipids, alpha-tocopherol, and malondialdehyde were monitored in type 1 diabetes mellitus patients for 8 hours after a standard fat-rich breakfast and lunch. Although glucose and triglycerides increased, alpha-tocopherol decreased and malondialdehyde increased in the postprandial phase. In the postabsorptive phase values returned to fasting levels. These results point to the possible relevance of postprandial alpha-tocopherol depletion and lipid peroxidation to an increased cardiovascular risk in these patients.

Published 8 March 2005 in Ann N Y Acad Sci, 1031: 439-42.
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