Vitamin E Research Today is a free monthly online journal that collates and summarizes the latest research about Vitamin E, including details on benefits, dosage, supplements, antioxidants.

Effect of vitamin E or metformin for treatment of nonalcoholic fatty liver disease in children and adolescents: the TONIC randomized controlled trial.

Lavine JE, Schwimmer JB, Van Natta ML, Molleston JP, Murray KF, Rosenthal P, Abrams SH, Scheimann AO, Sanyal AJ, Chalasani N, Tonascia J, Ünalp A, Clark JM, Brunt EM, Kleiner DE, Hoofnagle JH, Robuck PR,

Department of Pediatrics, Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Columbia University, New York, New York, USA. jl3553@columbia.edu

Published 27 April 2011 in JAMA, 305(16): 1659-68.
Full-text of this article is available online (may require subscription).

Articles on Vitamin E published 27 April 2011:

Effect of vitamin E or metformin for treatment of nonalcoholic fatty liver disease in children and adolescents: the TONIC randomized controlled trial.   JAMA, 305(16): 1659-68.

[Abstract] [Full-text]

Articles on Vitamin E published 9 March 2011:

Gamma-tocotrienol as an effective agent in targeting prostate cancer stem cell-like population.   Int J Cancer, 128(9): 2182-91.

Emerging evidence supports that prostate cancer originates from a rare subpopulation of cells, namely prostate cancer stem cells (CSCs). Conventional therapies for prostate cancer are believed to mainly target the majority of differentiated tumor cells but spare CSCs, which may account for the subsequent disease relapse after treatment. Therefore, successful elimination of CSCs may be an effective strategy to achieve complete remission from this disease. Gamma-tocotrienols (γ-T3) is one of the ... [Abstract] [Full-text]

Articles on Vitamin E published 3 March 2011:

New synthetic route to N-tocopherol derivatives: synthesis of pyrrolopyridinol analogue of α-tocopherol from pyridoxine.   Org Biomol Chem, 9(6): 1749-55.

A new synthetic route to pyrrolopyridinol antioxidants from easily accessible pyridoxine was developed which includes phase-transfer catalytic alkylation and intramolecular Cu(I)-catalyzed amination as key steps. [Abstract] [Full-text]

Articles on Vitamin E published 25 February 2011:

Vitamin E and adiponectin: proposed mechanism for vitamin E-induced improvement in insulin sensitivity.   Nutr Rev, 69(3): 155-61.

Insulin resistance and type 2 diabetes have been treated with the PPARγ agonists thiazolidinediones, or TZDs, since the 1990s. One mechanism by which these drugs may work is through PPARγ-mediated upregulation of adiponectin, an endogenous adipokine that has been shown to increase insulin sensitivity. Interestingly, α- and γ-tocopherol, two vitamin E vitamers, have structural similarities to the TZDs and have also been linked to enhanced insulin sensitivity. A recent study identified a ... [Abstract] [Full-text]

Articles on Vitamin E published 22 February 2011:

Pretreatment with anti-oxidants sensitizes oxidatively stressed human cancer cells to growth inhibitory effect of suberoylanilide hydroxamic acid (SAHA).   Cancer Chemother Pharmacol, 67(3): 705-15.

[Abstract] [Full-text]

Articles on Vitamin E published 21 February 2011:

Polymorphisms in the CD36/FAT gene are associated with plasma vitamin E concentrations in humans.   Am J Clin Nutr, 93(3): 644-51.

[Abstract] [Full-text]

Articles on Vitamin E published 17 February 2011:

Vitamin E for neuroleptic-induced tardive dyskinesia.   Cochrane Database Syst Rev, 2: CD000209.

[Abstract] [Full-text]

Articles on Vitamin E published 1 February 2011:

Reduction of radiation-induced vascular nitrosative stress by the vitamin E analog γ-tocotrienol: evidence of a role for tetrahydrobiopterin.   Int J Radiat Oncol Biol Phys, 79(3): 884-91.

[Abstract] [Full-text]

© 2004-2011 Vitamin E Research Today. All Rights Reserved.